Abstract

STUDY OF ANTHELMINTIC ACTIVITY OF CHLOROFORM EXTRACT OF TINOSPORA CORDIFOLIA

Shraddha D. Pawar*, Yamini B. Patil ,Laxmi A. Premchandani, Sandhya L. Borse,Dr. Laxmikant B. Borse, Dr. Sunil P.Pawar

ABSTRACT

The present study aimed at the in-vitro evaluation of anthelmintic activity of chloroform extracts of stem of Tinospora cordifolia using Eisenia foetida at four different concentrations (10, 25, 50 and 100 mg/ml) respectively. The study involved the determination of time of paralysis (P) and time of death (D) of the worms. At the concentration of 100 mg/ml the chloroform extracts exhibited very significant activities as compared to the standard drug Albendazole (10 mg/ml). The time of paralysis and death was recorded as 3.17±0.28 and 9.82 ± 0.58 in chloroform extract respectively. In conclusion, the use of stem of Tinospora cordifolia as an anthelmintic has been confirmed.

Keywords: Tinospora cordifolia, Anthelmintic, Eisenia foetida, Chloroform extract, Albendazole.