Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS SEPTEMBER ISSUE PUBLISHED
  • SEPTEMBER 2020 Issue has been successfully launched on 1 September 2020.

Abstract

IN VITRO ANTIARTHRITIC AND HEMOLYSIS PREVENTIVE: MEMBRANE STABILIZING EFFICACY OF ETHANOLIC ROOT EXTRACT OF OPERCULINA TURPETHUM

*Veena Sharma, Manu Singh

Department of Bioscience and Biotechnology, Banasthali University, Banasthali 304022, Rajasthan, India.

ABSTRACT

Operculina turpethum Linn is convolvulaceous plant which is found throughout India, China, Ceylon, Australia. The roots are bitter, acrid, thermogenic, purgative, carminative, antihelmintic, expectorant, antipyretic, hepatic, stimulant and hydragogue. They are useful in colic constipation, dropsy, vitiated conditions of vata, paralysis, myalgia, arthralgia, pectoralgia, bronchitis, obesity, helminthiasis, gastropathy, ascites, inflammations, intermittent fever, leucoderma, puritus, ulcers, erysepelas, haemorrhoids, tumors, jaundice, ophthalmia, employed in drug formulations, dropsical effusions and rheumatism. In this study, membrane stabilizing properties of ethanolic root extract of the plant were investigated for their red blood cell membrane stabilizing potential. Membrane stabilization activity of ethanolic extract of Operculina turpethum roots was investigated against normal erythrocytes exposed to both heat and hypotonic induced lyses. The extracts inhibited heat as well as hypotonic solution induced haemolysis of erythrocytes in vitro. The percentage membrane stability exhibited by the extracts was concentration dependent and compared favorably with those of standard drugs as diclofenac and acetyl salicylic acid.

Keywords: Arthritis, diclofenac, hemolysis, hypotonic.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More