Abstract

AN OVERVIEW ON ARTIFICIAL BLOOD

S. S. Aher*, P. D. Kulat and R. S. Bachhav

ABSTRACT

The 21st century is challenging for human beings. Increased the growth of population, population aging, generation of new infectious agents, and natural disasters are some threatening factors for the current state of blood transfusion. Artificial blood is designed only for the purpose of transporting oxygen and carbon dioxide throughout the body. Depending on the type of artificial blood, it can be produced in different technology using chemical isolation, synthetic production, or recombinant biochemical technology. The technology focused on two major blood substitutes in pharmaceutical aspects are perfluorocarbons and hemoglobin-based oxygen carriers (HBOC’s). It is anticipated that when an artificial blood product is available, it will have annual sales of over $7.6 billion in the United States alone.

Keywords: Artificial blood, Hemoglobin, Hemoglobin-based oxygen carriers, Oxygen carrier, Perfluorocarbons, Red blood cells.