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Abstract

REVIEW ON MELATONIN – A MIRACULOUS DRUG AND ITS APPLICATIONS

Nirmal Milind Kasekar*, Gajendra J C Gupta, K R Jadhav, Vilasrao J Kadam

ABSTRACT

isolated in1958 from bovine epiphysis by Lerner. The secretion follows circadian pattern with high levels during the dark cycle. In addition to the pineal gland, melatonin is synthesized in several other structures -enterochromaffin cells, eye retina, peripheral teleneurons and the gastrointestinal tract. Melatonin is very popular as a sleep remedy and a natural treatment for insomnia. Studies show that it can be used as an antioxidant, cancer protective agent, skin protective agent, contraceptive and as a treatment for seasonal affective depression. There are other uses of melatonin, which are still being studied today

Keywords: Broad activity, melatonin, night hormone, pineal gland, tryptophan.


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