Abstract

INVITRO ANTI-INFLAMMATORY ACTIVITY OF MYXOPYRUM SMILACIFOLIUM BLUME (OLEACEAE)

Jolly Samu*, Siju E. N. , Minil M and Rajalakshmi G R. 

ABSTRACT

Inflammation can cause various physical dysfunctions. The study was aimed to evaluate the anti inflammatory activity of both ethanol and aqueous extract of the leaves of Myxopyrum smilacifolium Blume by HRBC membrane stabilization method and protein denaturation, using different concentrations (25, 50,100, 200 μg/ml). In this study membrane lysis and protein inhibition was taken as the measure of anti-inflammatory activity. Both results are compared with standard diclofenac, Myxopyrum smilacifolium showed significant membrane stabilizing activity of 69.60% and protein inhibition activity of 91.54% at concentration of 200 μg/ml. The result obtained from this study suggests that plant is a good natural source for anti-inflammatory therapy.

Keywords: Myxopyrum smilacifolium, Anti-inflammatory, HRBC, Protein denaturation.