Abstract

INTRAVENOUS LIPID EMULSION THERAPY

Poovitha T., Raima Sabu, Reshma Elizabeth Raju* and Shangavi V.

ABSTRACT

Intravenous lipid emulsion had become a most efficacious therapy procedure in order to treat cardiovascular collapse induced by local anesthetics. It acts by establishing an equilibrium, by generating an expanded intravascular lipid phase, which further steers the causative drug into a newly created ‘lipid sink’ from the target tissue. Hence, the lipid emulsion procedure is regarded as an inclusive method for reversing the toxicity generated by the overdosing of lipophilic drugs. Some cases with successful revival suggest that treating non-local anesthetic (beta-blockers, calcium channel blockers, pesticides, herbicides, and various psychotropic drugs) overdoses using the lipid emulsion infusion procedure very effective. Our review explains the accessible preparations, compositions, conduct, risks, and benefits in various administrations.

Keywords: It acts by establishing an equilibrium, by generating an expanded intravascular lipid phase, which further steers the causative drug into a newly created ‘lipid sink’ from the target tissue.