Abstract

A REVIEW ON THE RISKFACTORS AND COMPLICATIONS OF PEPTIC ULCER DISEASE

Ruksana Rahim*, Athulyaraj S., Archana Vijai and Santhosh M. Mathews

ABSTRACT

Peptic ulcers disease [PUD] are one of the most common gastrointestinal tract disorders. The recent past few decades have witnessed an increase in the rate of peptic ulcers occurrence in our human community. It has evidently been shown from available statistics that an approximated over 10 percent of the human population are extremely at risk of suffering from the disease at some point in their lifetime.A peptic ulcer is a sore wound or red erosion area on the coating lining of the stomach called gastric ulcer or the small intestine called duodenal ulcer.There are many effects of peptic ulcer in the human body.Such include recurrent pains along the gastrointestinal tract, vomiting, heartburns, poor appetite and weight loss.On the basis of findings,this review found the H. pylori and the use of NSAIDs are the most common risk factors for developing peptic ulcer disease,and also the genetic, stress and comorbidity increase the risk of PUD occurrence.There are four major complications of peptic ulcer disease: bleeding, perforation, penetration, and obstruction. Complications can occur in patients with peptic ulcer of any etiology.

Keywords: Peptic ulcer disease, Risk factors, Helicobactor pylori, Non steroidal anti inflammatory drugs, Complications.