Abstract

A REVIEW ON CONVENTIONAL TREATMENT OF PEPTIC ULCER DISEASE

Pasupuleti Neelima*, Pendyala Megana, Natta Prathiba and Kantamaneni Padmalatha

ABSTRACT

Peptic ulcer disease is the widespread disease, effecting around 5-10% of global population. However, based on significant and racial versions, two most common etiological reasons are persistent infection of H. pylori and usage of NSAIDs. Prognosis can be primarily based on endoscopy and lively such of H. pylori presence. Eradication therapy of H. pylori is pleasant preference to achieve final cure of peptic ulcer disease. Numerous global guidelines, recommended triple therapy as first line therapy which includes proton pump inhibitor, amoxicillin, clarithromycin. Combination therapy suggest the decreased efficacy over a period of time. Several new treatment options or changes are already established few years back to overcome the therapy. Primary purpose in growing the antibiotic resistance in the presence clarithromycin, metronidazole strains. The aim of this study is to describe the occurrence and primary therapeutic options of the peptic ulcer disease.

Keywords: Peptic ulcer disease. Pylori, NSAIDs, Proton pump inhibitors.