Abstract

A REVIEW ARTICLE ON FUTURE DEADLIEST VIRUS -MARBURG VIRUS

Dr. Shaik Bobby Parveen ?, Madamanchi Manjusha, Reddy Sucharitha, Athina Jahnavi, Sadasiva Rao Galaba

ABSTRACT

Marburg virus (MARV) is a highly pathogenic virus associated with severe disease and mortality rates as high as 90%. Outbreaks of MARV are sporadic, deadly, and often characterized by a lack of resources and facilities to diagnose and treat patients. There are currently no approved vaccines or treatments, and the chaotic and infrequent nature of outbreaks, among other factors, makes testing new countermeasures during outbreaks ethically and logistically challenging as was the case with Ebola, it is anticipated that future outbreaks of Marburg virus disease (MVD) will trigger interest in the use of investigational products. The clinical features and risks of spread of MVD closely resemble Ebola virus disease (EVD); Supportive care, infection control and other response measuresare identical. However, much less is known about MVD than EVD because there has not been a recent large-scale outbreak of MVD.

Keywords: Marburg virus (MARV), Filovirus, Human pathogenesis.