Abstract

REVIEW ON PHARMACOLOGICAL ACTIVITIES AND PHYSICOCHEMICAL ANALYSIS OF ZINGIBER OFFICINALE (GINGER) ALONG WITH ITS TLC, HPLC AND HPTLC PROFILE

Priti R. Neware*, Trinkal V. Manapure, Roshni Kamble, Sayyed Ahetesham Ali, Ayushi Puri, Pawan Chaudhari and Snehal Chaudhari

ABSTRACT

Ginger (Zingiber officinale Rosc.) is a well-known traditional medicinal plant used for therapeutic effects in both Unani and Ayurvedic System of Medicine. It has been founded to have many therapeutic activities such as anti-inflammatory, anti-rheumatic and anti-gout properties. It is also useful in the management of cough, dyspepsia, loss of appetite, relaxed sore-throat, retching, spasms / spasmodic affections of the stomach, vomiting. Methods: Organoleptic characters, extractive values, ash values, phyto-chemical analysis, TLC, HPTLC, fluorescence analysis and HPLC profile etc. were the parameters used for the standardisation of the test drug. e. The primary pungent agents are due to the presence of phenylalkylketones or vanillyl ketones. Gingerol and shogaol are two most active constituents of ginger based preparations. Ginger has a long history of medicinal use dating back 2,500 years in China and India for conditions such as headaches, nausea, rheumatism, and colds. Characterized in traditional Chinese medicine as spicy and hot, ginger is claimed to warm the body and treat cold extremities, improve a weak and tardy pulse, address a pale complexion, and strengthen the body after blood loss. The present study aimed towards the evaluation of the parameters involved in the determination of the quality and purity of Zingiber officinale Rosc. rhizome and its standardization. The review article focuses on experimental advances in pharmacology of gingerol and its analogues.

Keywords: Medicinal Plant, Pharmacological effects, Phyto-chemical analysis, Quality, Standardization, Ginger.