Abstract

A REVIEW ON MOUTH DISSOLVING FILMS

P.M.M. Naga Lakshmi Varma*, Shaik Shaheda Begum and K. Padmalatha

ABSTRACT

Mouth dissolving film is the most advanced oral solid dosage form due to its flexibility and easy to use. Mouth dissolving films dissolve and disintegrate within a minute when placed in mouth without taking water or chewing. This dosage form allows the medication to bypass the first pass metabolism so bioavailability of drug may be improved. Mouth dissolving film has potential to rise onset of action decreases the dosing and eliminate the fear of chocking. Formulation of mouth dissolving films involves both the visual and characteristics as plasticized hydro colloids. API taste masking agents are being laminated by solvent casting and semisolid casting method. Solvent casting method being the most preferred method over other methods because it offers great uniformity of thickness and films prepared having fine glossy look and better physical properties. Mouth dissolving films are evaluated for its various parameters like thickness, physical property like folding endurance, disintegration and dissolution time. This review gives an idea about formulation techniques, evaluation parameters and some available marketed products of mouth dissolving film.

Keywords: Mouth dissolving films, solvent casting, fast disintegration.