Abstract

CLINICOPATHOLOGICAL STUDY OF TUMOURS AND TUMOUR LIKE LESIONS OF SYNOVIAL JOINTS

Dr. Sahana V. V.*, Dr. Rajendra Prasad K. N., Dr. Suja Ajoykumar, Dr. Suguna B. V.

ABSTRACT

Introduction: Synovium is a specialised mesenchymal tissue which reacts to wide variety of changes and noxious influences originating locally or elsewhere in the body. Most of synovial tumours show typical pathological features but have identical clinical findings. Hence histopathological study play a vital role in early diagnosis of these neoplastic synovial lesions. Clinical and radiological findings also helps in arriving at an exact diagnosis. Bjectives: To study histopathology of neoplastic synovial lesions. Material and Methods: 55 synovial biopsy specimens received in the Department of Pathology, KIMS, Bangalore during last two years (July 2014 - July 2016) have been taken for the study. A detailed histopathological study of the sections with relevant clinical and radiographic findings was analysed. Results: Out of 55 cases, 54 cases (98.2%) were benign and 1 case (1.8%) was malignant. Benign lesions included 35 cases (63.6%) of ganglion cysts, 8 cases (14.5%) of baker’s cyst, 5 cases(9.1%) of synovial lipomatosis and 6 cases (10.90%) of giant cell tumour of tendon sheath. Malignant lesion included a case of synovial sarcoma (1.8%). Histopathological features were correlated with clinical and radiological findings. Conclusion: Histopathological evaluation of neoplastic synovial lesions aids in categorising and accurately assessing neoplastic synovial lesions.

Keywords: Synovial lipomatosis, Synovial sarcoma, Baker’s cyst.