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Abstract

INSIGHTS OF HYPHENATED MASS SPECTROSCOPIC TECHNIQUE

A Anusha Mary*, Dinesh R. Chaple, Kumar Pratyush, Abhidnya Deshmukh and Vaibhav Mohare

ABSTRACT

Liquid chromatography–mass spectrometry (LC-MS) is a technology of emerging importance in many fields like in the field of pharmacology, drug development, proteomics etc. LC-MS approaches have shown tremendous potential in the field of drug development. Here are limitations and caveats to be considered when implementing this technology into the clinical laboratory environment. A review of methodological approaches, applications, Instrumentation, and its various interface types are discussed in this paper.

Keywords: Liquid Chromatography, Mass Spectroscopy, Interface, Proteomics, Metabolomics.


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