Abstract

MANAGEMENT OF CHRONIC KIDNEY DISEASE INDUCED COMPLICATION IN END-STAGE RENAL DISEASE PATIENTS

Suhas Reddy C.*, Bala Murali S. and Raja Rajeshwari B.

ABSTRACT

Introduction: Complication of Chronic Kidney Disease (CKD) is recognized as a major health problem, because of its resultant complication and its significant load on the patients affected and on health-care systems caring on them. At End-Stage Renal Disease (ESRD) the treatment option for most of the patients is Kidney Transplantation or Dialysis. CKD patients are associated with many electrolyte and mineral metabolism abnormalities, other body fluids and end result in number of complications. Dialysis-dependent, End-Stage Renal Disease patients will be having higher medication burden. Hence the effect of this medications should be studied to reduce the complications and to improve the patient’s quality of life. Aim: To evaluate the, management of complication in CKD (ESRD) patients undergoing hemodialysis. Methodology: This was a prospective observational study, were a total of 100 patients on hemodialysis (maintenance) were studied for a period of 9 months in Department of Nephrology at a south Indian hospital. Results: Majority of patients belongs to an age group of 41 – 50 years (47%), which includes 77% males and 23% females. Majority of the patients have three complication. A huge total of 700 drug was used for management of various complications of CKD with average of 8.02 ± 1.8 drugs per prescription. In that majority were 27.7% on Antianemic’s followed by 16.1% of Antihypertensives. Conclusion: Management of CKD induced complications had rational complex drug regimens which is evident from the dosing trend noticed by the study. Anemia, hypertension, hyperuricemia are the major complications seen in majority of the study population.

Keywords: Chronic Kidney Disease, Complications, End-Stage Renal Disease, Anemia.