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Rishikesh Sharma* and Gurdeep Singh


Introduction/Objectives: The main objective of this study is to determine efficacy of Amaranthus Spinosus for identification of chemical compounds, used for determine the antimicrobial activity using different models. Methodology: Phytochemical compound, Agar Plate Method, GC-mass spectrometry instrument were used to detected the chemical compound for the antimicrobial activity. Different model used for determine the antimicrobial property of the Amaranthus Spinosus. Results: In this study data show ethanolic extract of the Amaranthus Spinosus show significant reduction in microbial growth inhibition using agar plate method, phenolic compound presence and flavonoid present. GC-mass study support the presence of antimicrobial drugs like Benzoic acid, O-Amino benzohydrosanilic acid, 2-Aminobenzoyl hydrazide, Benzoic acid, 2-hydroxy acetyl acetate which have significant anti-microbial activity. Conclusion: The studies data support significant anti-microbial activity using ethanolic extract of Amaranthus Spinosus leaves for anti-microbial activity. The formation of suitable dosage form by isolate phytochemical compound which responsible for anti-microbial activity and use on the animal models will be increase the chance of better results.

Keywords: Amaranthus Spinosus, GC-mass, Isolate Phytochemical Compound, Anti-microbial activity,

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