Abstract

THE EFFECT OF PROBIOTIC AND COLISTIN SULPHATE ON INFECTION WITH SALMONELLA ENTERITIDIS IN THE BROILERS

Ahmed Mohamed El Mahdy*, Jihan Mostafa Badr and Mogda Kamel Mansour

ABSTRACT

The current research looked into the effects of consuming Bacillus Coagulans spores-based probiotic in the ration and/ or colistin sulphate supplementation in drinking water on Salmonella Enteritidis intestinal colonization, immunoglobulin's formation, weight gain, clinical signs, and mortality rate of broiler chicks. One hundred Salmonella-free, 1 day-old, cubb chicks were divided to 5 equal groups (20 hicks per group). Chicks in groups 2, 3, 4, and 5 were infected orally with 10×106 cfu/ml of Salmonella Enteritidis field strain given on the 3rd day of age. Chicks in group 1 were neither infected nor treated (negative control). Chicks in the 2nd group were infected with Salmonella Enteritidis (positive control), while chicks in the 3rd group were received Bacillus Coagulans spores-based probiotic. Chicks in group 4 were given colistin sulphate and chicks in group 5 were given both Bacillus Coagulans spores based probiotic and colistin sulphate. Using student T-test, statistical analysis for results of intestinal colony count of Salmonella Enteritidis revealed a highly significant decrease (P

Keywords: Bacillus Coagulans spores based probiotic, colistin sulphate, Salmonella Enteritidis, immunity and broiler.