Abstract

ANTI ANAEMIC ACTIVITY OF HYDRO ALCOHOLIC EXTRACT OF LEAVES OF ALLIUM TRICOCCUM IN PHENYL HYDRAZINE INDUCED AMNESIA IN RATS

Shekhar Priyanshu*, Joshi Ankur, Malviya Sapna & Kharia Anil

ABSTRACT

The aim of the current study is to gauge the anti-anaemic activity of hydro alcoholic leaves extract of Allium Tricoccum against phenyl hydrazine evoked anaemic rats. The anaemia was evoked in rats by the administration of phenyl hydrazine (10 mg /kg) intraperitoneal for two days. The animals were divided into five different cluster of 6 animals each. Cluster I served as traditional management, Cluster II as anaemic management, Cluster III as management administered with vitamin B and Cluster IV animals were treated with 100 mg /kg, Cluster V animals were treated with 200 mg/kg, of hydro alcoholic leaves extract of Allium Tricoccum. All the test drugs and standard Drugs were administered once daily for twenty eight days through oral route. On twenty ninth day blood was withdrawn, through sinus puncture underneath Luminal anaesthesia and subjected to the estimation of erythrocyte, haemoglobin and proportion Haematocrit. Each the hydro alcoholic leaves extract of Allium Tricoccum and vitamin B12 considerably redoubled the erythrocyte, haemoglobin and Haematocrit levels that conclude the, Allium Tricoccum fruit extract exhibits anti-anaemic activity.

Keywords: Anaemia, anti-anaemic activity, hydro alcoholic extract, Allium Tricoccum, Vit. B12.