Abstract

LITERARY REVIEW ON ANTI-INFLAMATORY AND BRONCHODILATORY ACTIVITY OF SIMHYADI KWATHA W.S.R. TO SHWASA

Dr. Radha Naik* and Dr. Raman Belge

ABSTRACT

Shwasa roga is a respiratory disease mentioned in Ayurvedic texts. The provoked Vata enters the Pranavaha Strotasa gets vitiated and rouses up the Kapha present in the Uraha. Obstruction of the Pranavayu and Strotovaigunya produces Shwasa. As per modern medicine Shwasa may be correlated with Asthma. Asthma is a chronic disease of respiratory system. The prevalence of asthma has been estimated to range between 3% - 38% in children and 2% - 12% in adults. The inflammation of the airway, bronchial hyperresponsiveness and intermittent airflow obstruction are pathophysiological features of asthma. Antigen antibody complex attachment to the mast cell causes its disruption releasing inflammatory mediators like histamine. To evaluate the efficacy of anti-asthmatic property of a drug, assessment of mast cell stabilizing, anti-histaminic and bronchodilator property can be used as pharmacodynamic parameter. Ayurveda is highly effective in treating many chronic diseases like Shwasa. Thus an attempt has been made to evaluate the probable efficacy of polyherbal Simhyadi Kwatha mentioned in Yogratnakar Vol 2, Shwasa rogadhikar in treating Shwasa. Aim and Objective: To study the Anti-inflamatory and Bronchodilatory Activity of Simhyadi Kwatha w.s.r. to Shwasa. Material and Methods: The Ayurvedic classics, research articles, online journals were thoroughly reviewed to compile relevant and scientific data about Simhyadi Kwatha and its ingredients. Observation and Result: The review of Ayurvedic classics, research articles, online journals have proved the bronchodilator, anti-histaminic, anti- tussive, bronchorelaxant, anti- inflammatory activity of the ingredients of Simhyadi Kwatha. Conclusion- Simhyadi Kwatha is a polyherbal formulation. This review presents collective knowledge of its pharmacological, therapeutic action and probable anti- asthmatic effect. Thus Simhyadi Kwatha can be safely prescribed to the patients suffering from Shwasa.

Keywords: Anti-histaminic, Anti-inflamatory, Asthma, Bronchodilator, Simhyadi Kwatha, Shwasa.