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*Tiwari H. S., Barfa Rajendra, Mehta Pooja, Alam Anzar, Panda B. P., Kumawat Ram Achala, Padhar C. Kumar Bharat and Mangal Gopesh


Objectives: To Evaluate The Efficacy of Pachmeena Tonic In The Management of Ajeerna. Methods: The total of 50 subjects were enrolled, and informed consent was taken. The subjects were instructed regarding the study procedure and were advised to take Pachmeena Tonic for 15 days. Patients were assessed based on their clinical presentations on the dates i.e., Day 0, Day 15 and Day 30.Primary End-Point Assessment: The changes in Acid Regurgitation were assessed at pre-treatment (Day 0), at the end of treatment (Day 15) and after follow-up (Day 30).The secondary outcome (other subjective parameters, as per validated symptom severity grading criteria for the patients with Ajeerna (Indigestion), developed by Hu WH, Wong YH et al. (J Gasteroenterol Hrpatol 2002; 17(5): 545-51.) was assessed on Day 0, Day 15 and after Follow up (Day 30). Results: Efficacy of Pachmeena Tonic in Ajeerna (Indigestion) in Acid Regurgitation is analysed between before treatment (BT 0 D) at 0 day and After Treatment (AT 15D) at 15 day. Acid Regurgitation is found to be significantly reduced (p< 0.05) at 15th day of treatment (P= 0.0062; t=2.833). Secondary End Point Assessments: There was improvement seen in all the other clinical parameters of Ajeerna (Indigestion) like Heart burn, feeling of acidity etc. post completion of trial. Conclusion: The present study shows that the subjects taking Pachmeena tonic showed improvement in symptoms of Ajeerna (Indigestion).

Keywords: Pachmeena, Ajeerna, Indigestion, Acid Regurgitation.

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