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Jayashree Ramesh Diwate* and Prof. D. T. Panjwani


Topical administration for visual therapeutics is directly because smaller doses required compared to the systemic use, its rapid onset of action and freedom from systemic toxicity Topically applied visual drugs need to reach the inner parts of the attention and trans corneal penetration is believed to be the main route for drug absorption. Corneal absorption is much slower process than elimination. The particular aim of designing a therapeutic system is to achieve an optimal concentration of a medication at the active site for the appropriate duration. Ideal ophthalmic drug delivery must be ready to sustain the drug release and to stay within the vicinity of front of the attention for prolong period of your time. Therefore, it's basic to optimize ophthalmic drug delivery; one among the thanks to do so is by addition of polymers of differed grades, development of in place gel or sol or using erodible or non-erodible insert to prolong the pre corneal drug retention. This review focused on controlled and sustained drug delivery has become the quality in modern pharmaceutical design and a number of other possible routes of drug delivery into the ocular tissues.

Keywords: Ophthalmic Drug, Corneal drug delivery, Eye-Drop, Controlled and sustained drug delivery.

[Full Text Article]

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