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  • WJPPS APRIL ISSUE PUBLISHED
  • APRIL 2021 Issue has been successfully launched on 1 April 2021.

Abstract

ETHOSOMES: A UNIQUE NANOCARRIER FOR DRUG DELIVERY

K. C. Prajwal*, A. R. Shabaraya and K. Vineetha

ABSTRACT

Recent studies have created ethosomes, a novel lipid carrier. Ethosomal systems are ethanol-carrying lipid carriers that improve permeation. Ethosomes, including deformable liposomes, have been shown to have high encapsulation power effectiveness. For a broad variety of molecules, including lipophilic drugs, skin deposition ability and depth of skin penetration are successful at transporting molecules to and through the skin. Molecular transmission via the biological membrane has become a major subject of study in biomedical research, whether for medicinal purposes, gene therapy, vaccination, or cellular transformations in recent years. Ethanol enhances the lipid fluidity of the cell membrane, allowing the ethosomes to enter the skin more easily. Within the skin, these ethosomes permeate and fuse with cells membrane lipids are released, and the drug is released. Ethosomes are produced using both hot and cold methods. Parameters for evaluation scale, shape, drug material, zeta potential, and so on. Ethosomes have been tested and found to be effective. Many such as cyclosporine A, insulin, salbutamol, trihexyphenidil, and others, are administered using this form. Ethosomes have a variety of significant advantages including increasing medication effectiveness, improving patient compliance and comfort, and lowering overall care costs. In the future, ethosomes can be an effective drug delivery method.

Keywords: Ethosomes, Ethanol, Nanocarriers, Transdermal delivery.


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