Abstract

ANTIMICROBIAL EMULGEL: A NOVEL DRUG DELIVERY SYSTEM FOR THERAPEUTIC USAGE

Namrata Patel*, Amresh Gupta, Arpita Singh and Nitish Kumar

ABSTRACT

Antimicrobial agents can kill cells immediately. Some antimicrobial cells sometimes even coagulate substances within the cell thus, massacring it. Antibiotic –free natural polymer based antimicrobial emulgels were discussed in this article. A cross-linked three dimensional polymeric combination of gel and emulsion is called as emulgel. The drug can be mounted into an emulgel and then released across a spectrum of procedures, including diffusion regulation, swelling control, chemical control and environmental response. Antimicrobial emulgels do not have specific mechanism of working; rather they show their action through various ways, such as through microbial protein biosynthesis, cell- wall biosynthesis, and destruction of microbial membrane. This review focuses on emulgel formation for antimicrobial agents that could be a viable alternative to conventional antibiotics by offering enhanced bioavailability, shielding, absorption, regulated and target release for integrated or surface absorbed drugs.

Keywords: Antimicrobials, Emulgel, Microbial membrane, Antibiotics.