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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

Call for Paper

WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

ANALYTICAL METHODS OF LOPINAVIR-A REVIEW

*R. Mounika, K. Alekhya, V. Sowmya Sri, K. Bhagyasri, M. Vamsi Krishna and K. Padmalatha

ABSTRACT

Lopinavir is a protease inhibitor and is used in combination with other antiretroviral drugs for the treatment of HIV-1 infection. Lopinavir is used exclusively in combination with ritonavir. This combination was first marketed by Abott. The combination is necessary because the lopinavir has poor oral bioavailability and extensive biotransformation. Ritonavir is a potent inhibitor of the enzymes responsible for lopinavir metabolism, and its co-administration "boosts" lopinavir exposure and improves antiviral activity. Analytical methods available for the estimation of lopinavir are presented in this review.

Keywords: Lopinavir, Analytical methods, Review.

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