Abstract

AN OVERVIEW ON OPTHALMIC DRUG DELIVERY SYSTEMS

*Vivek Kumar Varma, Dr. Anuj Agarwal, Suryakant Verma and Dr. Sachin Tyagi

ABSTRACT

Over the past fifty years, ophthalmic drug supply study has made tremendous progress, questioning scientists on the benefits and disadvantages of this drug supply approach. Topical eye drops are the most popular formulation in the delivery of ocular drugs. Despite strong tolerance for patients, this topical treatment focuses only on earlier eye disorders, with high precorneal medication losses due to the development of tears and eye barriers. Antibiotics are often used in the ophthalmic route in solution or ointment. However, their local bioavailability needs to be improved to decrease the administrative frequency and adverse reactions and enhance their therapeutic effectiveness. For this reason, continuous-release forms for ophthalmic antibiotic delivery have been created. This examination briefly explains the eye administration with the eye barriers and existing topical shapes. The aim is to overcome the limitations of ocular antibiotic delivery using the latest ocular technologies as colloidal and in situ gelling systems or improve existing types as implants and contact lenses. Nanotechnology is now a promising way to protect antibiotics and develop the pathway through ocular barriers and deliver drugs to unique target sites.

Keywords: Antibiotics, Ocular Drug, Nanoparticles, Drug Particles.