Abstract

QUALITY ASSESSMENT OF A TRADITIONAL OIL BASED AYURVEDIC POLYHERBAL FORMULATION FOR KHALITYA: YASHTIMADHU TAILA

Chandani D. Chauhan* and D. B. Vaghela

ABSTRACT

Introduction: Hair fall is a physiological phenomenon, generally, after the mid-forties, but it is considered as a disease if it occurs before this period. Ayurveda texts describe hair fall under Shirogata Rogas (diseases of head) under the broad heading of Khalitya. Yashtimadhu Taila has been described in Chakradatta to be used in Khalitya (hairfall) and Palitya (graying of hair) as a nasal administration medicine. In the present study, attempt has been made to assess the quality of Yashtimadhu Taila and to establish the quality control standards for the same. Objectives: The objective of this study was carried out to standardize the finished product Yashtimadhu Taila to confirm its identity, quality, and purity. Materials and Methods: Yashtimadhu Taila was prepared as per Snehapaka Kalpana mentioned in Sharangadhara Samhita. Organoleptic properties (color, smell, appearance, and taste) and physicochemical parameters (specific gravity, saponification value, refractive index, acid value and iodine value) were determined to assess the quality of this oil using standard protocols. High performance thin-layer chromatography (HPTLC) fingerprint was developed for oil. Results: Yashtimadhu Taila appeared to be dark golden yellow viscous oil with characteristic slightly aromatic sweetish sesame oil odor and bitter-astringent taste. In addition, saponification value (mg/g) was 178.7, acid value (%) was 0.488, iodine value (I2 100/g) was 82.91, specific gravity at room temperature was 0.9181 and refractive index was 1.482 respectively. HPTLC profile of the methanolic extract of the drug showed 7 spots at 254nm and 4 spots at 366 nm under UV light. Conclusion: The present study reveals the quality of Yashtimadhu Taila for the first time. This study will be helpful to the establishment of safety profile, efficacy, and acceptance of classical and parameters observed can be used as a reference for further research studies.

Keywords: Pharmacognosy, Pharmaceutical study, Khalitya, Yashtimadhu Taila, HPTLC