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  • WJPPS NOVEMBER ISSUE PUBLISHED
  • NOVEMBER 2020 Issue has been successfully launched on 1 November 2020

Abstract

ANTI MICROBIAL EVALUATION OF NEW OXADIAZOLE DERIVATIVES

Chilumula Nageshwar Rao*, K.Blessi Priyanka, J.Ravi, G.Dayakar*

ABSTRACT

5-(2-(2-(arylideneamino) oxazol-5-ylamino) benzoxazol-5-yl)-3- ((dialkylamino) methyl)-1, 3, 4-oxadiazol-2(3H)-thiones (XI) derivatives were evaluated for antimicrobial activity by using disc fusion method.The synthesized derivatives were evaluated for antibacterial activity and antifungal by using Ampicillin sodium and Clotrimoxazole as a standards. Among all compound XIa, XIb and XIh are more effective against bacteria. Among the series compound XIb is exhibited more inhibition against A.niger and C.albicans.

Keywords: Bezoxazole, Oxadiazole, antimicrobial, antifungal, antibacterial.


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