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Abstract

PILOT PLANT SCALE UP TECHNIQUES FOR THE PARENTRAL PREPARTIONS

Rahinj Dipali Eknath*, Rokade V. G. and Hingne L. D.

ABSTRACT

Pilot scale up techniques for the parentral preparation will provide guide line forthe manufacture of large scale process and this will play a pivotal role in large scale manufacturing. The Pilot plant is a relative term in the sense that pilot plants are typically smaller than full-scale production plants, but are built in a range of sizes. Also, as pilot plants are intended for learning, they typically are more flexible, possibly at the expense of economy. Some pilot plants are built in laboratories using stock lab equipment, The past two decades particular have witnessed amazing inventions and innovations in pharmaceutical research, resulting in the ability to produce new drugs faster than even before. The new drug applications (NDAs) and abbreviated new drug applications (ANDA) are all-time high. The preparation of several clinical batches in the pilot plant provides its personnel with the opportunity to perfect and validate the process.

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