Photo Gallery



News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.



Fawzia Z. El-Ablack*, Faten Z. Mohamed, Usama B. Elgazzar and Mahmoud M. Ramzy


Background: Diabetes mellitus (DM) is a group of metabolic disorders characterized by chronic hyperglycemia resulting from relative or absolute insulin de´Čüciency with or without insulin resistance. Aim: This study was aimed to evaluate the role of new coumarin derivative (cromen) in treatment of alloxan induced diabetes in rats by. Methods: 50 adult male albino rats were divided into 5 groups. Group I (control group, rats were orally administered with 1 ml saline daily). Group II (DMSO group, rats were orally administered with 0.2 % DMSO for 40 days). Group III (standard group, diabetic animals treated with 100 mg/kg b.wt of metformin for 40 days orally). Group IV (therapeutic group, diabetic rats treated orally with 50 mg/kg b.wt of cromen for 40 days). Group V (positive control, animals were injected intraperitoneal with 150 mg/kg b. wt. alloxan). At the end of experimental period blood serum, liver, kidney and pancreatic tissues were collected. Results: diabetic rats showed significant increase in the mean level of blood Glucose, serum ALT, AST, Total bilirubin, Urea, Creatinine, Cholesterol and triglyceride. Also, significant decrease in ALB level in compared to control group. In group treated with cromen there was significant decrease in elevated biochemical parameters. Also, significant increase ALB level when compared with diabetic rats. Our results were confirmed by histopathological examination of different tissues. Conclusion: this study suggests that cromen exhibits anti-hyperglycemic and anti-lipidimic in alloxan induced diabetic rats.

Keywords: .

[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More