Abstract

G- PROTEIN-COUPLED RECEPTOR IN THE TREATMENT OF DIABETES: MATERIA MEDICA & DRUG ACTION

Varsha Singh*

ABSTRACT

One of the teams of metabolic disorders characterised by a high glucose over a drawn- out amount named polygenic disorder, normally remarked as polygenic disorder. Seven-(pass)-transmembrane domain receptors, normally remarked as G protein- coupled receptors (GPCRs). G-protein coupled receptors are the foremost vital receptor family inside the ordination because of their intrinsic properties, GPCRs represent the target of nearly 30% of approved therapeutic medication, together with polygenic disorder treatment. Hypoglycaemic agent resistance, a diminished ability of cells to retort to the action of hypoglycaemic agent, can be a key feature associated with the pathological process of metabolic disorder like polygenic disorder. The role of GPCRs in polygenic disorder in materia medica act as therapeutic targets of current and future glucose-lowering medication.

Keywords: Polygenic, Hypoglycaemic, Seven- pass-transmembrane, G protein.