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  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.

Abstract

A REVIEW: ANALYTICAL METHOD FOR DETERMINATION OF AZILSARTAN MEDOXOMIL IN PHARMACEUTICAL DOSAGE FORM AND BIOLOGICAL FLUID

Pranjali Shelke*, Rahul Godge and Mayur Bhosale

ABSTRACT

Azilsartan medoxomil is an antihypertensive drug used to treat hypertension in adults. It is selective angiotensin-II receptor antagonist. US Food and Drug Administration approved (Azilsartan Medoxomil Potassium) as antihypertensive. It belongs to class 4 category of BCS classification. Owing to low solubility and low permeability formulation and analytical method development becomes difficult. Analytical method plays vital role in physic-chemical properties description. This review includes most recent analytical methods such as various spectroscopic methods (simultaneous estimation, Q-absorption ratio) and chromatographic methods (RP-HPLC, HPTLC) for determination of azilsartan in various pharmaceutical dosage forms and biological matrix were reported.

Keywords: Azilsartan RP-HPLC, UV-Visible spectroscopy, HPTLC.


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