Abstract

EVALUATION OF DRUG PRESCRIBING PATTERN IN CHRONIC KIDNEY DISEASE PATIENTS AT TERTIARY CARE HOSPITAL IN NORTHERN INDIA -AN OBSERVATIONAL STUDY

Purna Atray*, Irfanul Haque, Sarita Jangra Bhyan, Kartikey Pathak and Anjali

ABSTRACT

Aim- The primary intent of the study is to analyze the prescribing pattern and to identify the various drug-drug interactions (DDIs) associated with the therapy in chronic kidney disease (CKD) patients. Methods- A total of 214 chronic kidney disease and transplantation patients were finally recruited after strictly obeying the selection criteria in this observational study that was conducted over a period of 6 months in Nephrology Department of multi-speciality hospital. Relevant data were extracted from prescriptions. Results- Mean age calculated was 51.51 ±16.07 (Mean ± SD) years with male predominance (69.15%). Hypertension (33.17%) and Diabetes (26.63%) are the most common comorbidities. Average number of drugs prescribed per prescription was 7.83. On the basis of first anatomical level of ATC classification, drugs from blood forming agents were highly recommended class of drugs (20.15%), followed by cardiovascular system agents contributing (19.08%), and drugs from alimentary tract and metabolism were (17.94%). Conclusion- This study demonstrates the variability of drug utilization in CKD patients. Cardiovascular agents were most commonly utilized followed by blood forming agents and nutritional supplements. High number of medications were used per prescription in this study thus increasing the possibility of drug interactions.

Keywords: Chronic kidney disease, prescribing pattern, Comorbidities, Drug utilization, Drug-drug interactions.