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Abstract

A STUDY ON MONITORING AND DETECTION OF ADVERSE DRUG REACTION AT GOVT. DISTRICT HEAD QUARTERS HOSPITAL, OOTY

Shalini Ravikumar* and Ponnusankar Sivasankaran

ABSTRACT

Introduction: Adverse drug reactions (ADRs) are considered as one among the leading causes of morbidity and mortality. It was analyzed that nearly 2.9-5.6% of people admitted in the hospitals are due to the ADR’s around 35% of people experience during their hospital stay. Aim & Objective: To conduct a Pharmacovigilance study among in-patients at Government Hospital, Ooty. Detection ADRs by using prospective method at practice site and educate the healthcare professional about ADRs. Materials and Method: A Prospective observational study was conducted at our hospital for a period of nine months of study. The patients admitted because of drug abuse, intentional & accidental poisoning (overdose) were excluded from the study. Result: A total of 800 patient’s medication chart review in which 470 were female and 330 were males. Among them 85 suspected adverse drug reactions (ADRs) were reported throughout the study period. Different factors such as the patient demographics, most commonly affected organ system; types of ADRs, outcome of management related to ADRs, seriousness, causality, preventability and severity assessment of ADRs were analyzed. Our results show that most of the ADRs were probably preventable therefore patients were given with ADR Alert Card for the further prevention and educated them about the ADR. Discussion: Adverse Drug Reactions (ADRs) monitoring and reporting programmes target to identify and measure the risks associated with the drug use. Identifying such adverse drug reactions will reduce the overall health care cost as well as improves patient’s safety.

Keywords: Adverse drug reactions (ADRs), Reporting, Pharmacovigilance (PvPI), Prospective method.


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