Abstract

A CORONA VIRUS: - GLOBAL CHALLENGE

Ashwini Nandkumar Gadage* and Akshata Popatrao Jagtap

ABSTRACT

Coronaviruses are a group of viruses enveloped with unsegmented, single-stranded, positive sense RNA. genomes. In addition to infecting a variety of economically important vertebrates (such as pigs and chickens), six Coronaviruses are known to infect human hosts and cause respiratory illness. Among them, acute bass Coronavirus respiratory syndrome (SARS-CoV) and Middle East coronavirus respiratory syndrome (MERS-CoV) are zoonotic and highly pathogenic coronaviruses that have caused regional and global epidemics Coronaviruses have a distinctive morphology, the name derives from the outer strip or "crown" of built-in envelope proteins. Members of the family Coronaviridae cause a wide spectrum of animals and humans. diseases. Uniquely, RNA genome replication proceeds through the generation of a nested pool of viral mRNA molecules. Human coronavirus (HCoV) infection causes respiratory illnesses with mild to severe results. In In the last 15 years, we have seen the emergence of two highly pathogenic zoonotic HCV: Coronavirus respiratory syndrome (SARS-CoV) and coronavirus Middle Eastern respiratory syndrome (MERS-CoV). HCV replication is regulated by a variety of host factors and induces drastic alterations in cell structure. and physiology. This review provides as much information (as possible) about Corona viruses.

Keywords: novel, severe respiratory tract infections, SARS-CoV-2 & a global health.