Abstract

THE EFECT OF SMOKING IN PARATHYROID HORMONE (PTH) AND ALKALINE PHOSPHTASE (ALP)

Noora Faroug , Elhashimi E. Hassan*, Nassr Eldin M.A.Shrif , Siham M.Bakhit

ABSTRACT

Background: Smoking is one of the most common practices and believed to be associated with decreased bone density and calcium absorption therefore abnormalities of both PTH and ALP are expected in smokers. Objectives: This study was aimed to study the effect smocking in serum levels of PTH and ALP activity in comparison to healthy non-smokers. Methods: this is a cross-sectional study conducted during the period from August to December 2011. Blood samples were drawn from 50 apparently healthy cigarette smokers’ volunteers (as test group) and 50 apparently healthy non smokers’ volunteers’ age, BMI and gender matched as control group. Serum levels of parathyroid hormone and ALP activity was analysed for both groups by using commercial reagent kits from DRG diagnostic and commercial reagent kits from Bio system Company by Selector E, respectively. Data were analysed using SPSS v 16. Results: The serum level of PTH in smokers (14.174±5.89 pg/ml) was significantly decreased than nonsmokers (26.874±11.8627 pg/ml) , p.value

Keywords: Background: Smoking is one of the most common practices and believed to be associated with decreased bone density and calcium absorption therefore abnormalities of both PTH and ALP are expected in smokers. Objectives: This study was aimed to study the eff