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  • WJPPS NOVEMBER ISSUE PUBLISHED
  • NOVEMBER 2020 Issue has been successfully launched on 1 November 2020

Abstract

A INFLIXIMAB MONOLOGUE: A CT-P13 BIOSIMILAR

Aakunuri Akhil*, Pisati Mounika Reddy, Dasoju Vamshi Krishna and Gubba Ramu

ABSTRACT

The reference anti-TNF-α antimicrobial infliximab is identical. In May 2015, all indications approved for reference infliximab, including rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriasis and sterilisation, were approved in the EU. The application is approved in this regard. In May 2015, it was approved. In many other nations, including Korea, the United States and Australia, this information has also been authorised. CT. P13 characterisation has shown close to reference infliximab in preclinical studies. In patients with mild to serious rheumatoid arthritis with methotrexate therapy CTP13 has demonstrated pharmacokinetic similarity to reference infliximab in healthy volunteers and clinically comparable effect. The safety and immunogenicity profiles were normally well tolerated; they were close to those of the infliximab comparison with no new safety issues found. Moving from infliximab reference to CTP13 does not affect clinical effectiveness, protection or immunogenicity. Relation infliximab plays a powerful role in treating autoimmune inflammatory disorders and CT.P13 offers an important biosimilar solution for patients who need infliximab treatment.[9]

Keywords: Infliximab, Biosimilar CT-P13, anti-TNF-? antibody.


[Full Text Article]

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