Photo Gallery



News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • JUNE 2021 Issue has been successfully launched on 1 June 2021.



Anuja S.*, Viresh K.C., Abdul Raheem T. and Shabaraya A.R.


Poor aqueous solubility and low oral bioavailability of an active pharmaceutical ingredient are the limitations during the growth of a new product. Co-crystal formation is a new approach to enhance the physicochemical properties of the active pharmaceutical ingredient. Co-crystallization with pharmaceutically acceptable compounds does not affect the pharmacological activity of the API but can improve the physical properties like solubility, stability and dissolution rate. Co-crystals are multi-component system of active pharmaceutical ingredient with a stoichiometric amount of a pharmaceutically acceptable coformer included within the crystal lattice. By manufacturing pharmaceutical co-crystals, the physicochemical properties of a drug can be improved thus it offers a great opportunity for the development of new drug products in the pharmaceutical industry. Most significantly, co-crystals can create new medicines with increased solubility and hence improve the efficiency and safety of the treatment. The main factor which affects co-crystal preparation is its thermodynamic stability. Screening of co-crystals gives details about the chemical structure and relation between active pharmaceutical ingredient and coformer. This review covers the different methods used for the synthesis of co-crystal such as grinding, slurrying, antisolvent, hot-melt extrusion, spray drying, etc. A brief description of characterization techniques routinely used for co-crystals and also its pharmaceutical applications has been incorporated here. Reported works on co-crystals were reviewed and have been briefly outlined here which further help to understand the concept of co-crystals in depth.

Keywords: Pharmaceutical co-crystals, co-crystallization, Dissolution rate, solubility, stability, solvent evaporation.

[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More