Abstract

SYSTEMATIC REVIEW ON: RISK FACTORS LEADING TO PEPTIC ULCER DISEASE

Purabi Saha*, Roshan Kumar, Binita Kumari, Sahenur Begum, Sibam Padhy, Vishnu Mittal, Nayan Kumar, Soumitra Sahana, Yogendra Kumar

ABSTRACT

Peptic ulcer usually happens once there's associate degree imbalance between aggressive stomachic factors (acid, pepsin, Helicobacter pylori, refluxed gall salts) and defensive membrane factors (gastric membrane barrier, carbonate secretion, speedy cell turnover, high blood flow). The treatment of ulcer is directed against reduction of aggressive factors or sweetening of membrane defense of abdomen and small intestine with cytoprotective agents. Additional recently, the role of membrane consider ulcer has received a lot of attention and also the term “Cyto protection” was 1st introduced by Andre parliamentarian in 1979. Generally it will be aforesaid that there's a excessiveness of mechanisms of stomachic cyto protection, their relative importance and reciprocality being aloof from clarity. This itself may be a purpose that stomachic cyto protection may be a complex development. The current paper enumerates the varied drug offered utilized in the treatment of ulcer. Emphazises ar created to co-relate the importance of assorted ancient system of medication used.

Keywords: Peptic ulcer disease, Risk factors, Helicobacter pylori, Non-steroidal anti-inflammatory drug.