Abstract

COMPARATIVE STUDIES ON SUSPENDING PROPERTY OF TRIBULUS TERRESTRIS MUCILAGE

Aachal Kolhe*, Apurva Deshmukh, Prof. Sohani Solanke, Dr. Mukund Tawar

ABSTRACT

Natural excipients can serve as alternative to synthetic products because of local accessibility, biodegradability, ecofriendly nature and cost effectiveness as compared to synthetic products. Therefore, it is a current need to explore natural excipients that can be used as an effective alternative excipient for the formulation of pharmaceutical dosage forms. The suspending property mucilage was evaluated comparatively with Acacia, compound tragacanth and NaCMC at different concentrations in calcium carbonate suspension, sulphamethoxazole suspension and zinc oxide suspension. Characterization tests were carried out on purified Tribulus terrestris mucilage. Sedimentation profile, redispersibility, rheology, particle size analysis were employed as an evaluation parameters. The values obtained were used as basis for comparison of the suspending agents studied. The results obtained indicated that the mucilage of Tribulus terrestris leaves could be used as a suspending agent, and the performance was found to be superior to acacia, compound tragacanth and NaCMC.

Keywords: Tribulus terrestris mucilage, compound tragacanth, NaCMC, sulphamethoxazole, Calcium carbonate, Zinc oxide.