WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

SIMULTANEOUS ESTIMATION OF ARTEROLANE MALEATE AND PIPERAQUINE PHOSPHATE BY RP-HPLC

Chinna Vagya Naik Mudavath*, K. Thejomoorthy and P. Sreenivasa Prasanna

ABSTRACT

A simple, precise, reliable, rapid and reproducible reversed-phase high performance liquid chromatography method was developed and validated for the simultaneous estimation of Arterolane Maleate, Piperaquine phosphate Chromatography is carried out isocratically on Xbridge C18 (250 × 4.6 mm, 5μm)with a mobile phase composed of 0.1% OrthoPhosphoric Acid and Acetonitrile (in the ratio of 90:10 (v/v) at a flow rate of 0.9 ml/min. Detection was carried out using a PDA detector at 290 nm. Parameters such as linearity, precision, accuracy, recovery, specificity and ruggedness are studied as reported in the ICH-Q2 (R1) guidelines. The retention times of Arterolane Maleate (ALM) and Piperaquine Phosphate (PQP) are 2.97, 6.97min respectively. The linearity range is 30-225 μg/ml for Arterolane and 150-1125 μg/ml for Piperaquine respectively. The correlation coefficients of ALM and PQP are 0.9975 and 0.9782. The proposed method can be useful in quality control of bulk Manufacturing and Pharmaceutical dosage forms.

Keywords: Arterolane Maleate and Piperaquine phosphate, HPLC, Validation, Retention time.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More