Abstract

A CASE OF SATOYOSHI SYNDROME: A MULTISYSTEM DISORDER

Arya O.* and Anmariya Babu

ABSTRACT

A 17-year-old girl with Satoyoshi syndrome is reported. Satoyoshi syndrome is a rare multisystemic disease of presumed autoimmune etiology characterized by progressive painful intermittent muscle spasms, diarrhea frequently associated with malabsorption, alopecia, skeletal abnormalities and endocrine disorders. Less than 50 patients with Satoyoshi syndrome have been reported in the world literature. This patient had alopecia, muscle spasms, and skeletal abnormalities, which are three of the most common clinical features of Satoyoshi syndrome. The girl with clinical and radiological features of the syndrome who has been successfully treated with prednisone and vit D supplemention and other supportive measures. In contrast to some reports, this patient failed to respond to intravenous immunoglobulin therapy. However, he responded dramatically to steroids. In her follow up, several months later, she attanined considerable improvement in her quality of life.

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