Abstract

GASTRO RETENTIVE DRUG DELIVERY SYSTEMS: CURRENT ADVANCEMENTS IN NOVEL SYSTEM DESIGN AND ASSESSMENT

Prateek Jain*, A.K. Singhai and Dilip K. Tiwari

ABSTRACT

Gastro-retentive drug delivery system (GRDDS) has acquired gigantic acceptance in the field of oral drug delivery in recent times. It is an extensively employed approach to retain the dosage form in the stomach for a prolonged period and release the drug slowly that can report many trials allied with conventional oral delivery, including poor bioavailability. Recently applied gastrointestinal technologies such as expandable, super porous hydrogel; bio/mucoadhesive, magnetic, ion-exchange resin; and low- and high-density-systems have also been examined along with their merits and demerits. This review covers the points of interest, disservices, advertised arrangement, and a few licenses of the Gastroretentive medication conveyance framework and speaks to the skimming and non-gliding Gastroretentive framework and features a portion of the current Gastroretentive methodologies.

Keywords: Gastroretentive, oral drug delivery, bioavailability, bio/mucoadhesive.