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Abstract

EVALUATION OF WOUND HEALING ACTIVITY OF ETHANOLIC EXTRACT OF STEM BARK OF CASSIA TORA LINN

Adib Alam*, Sailesh Narayan and Shailendra Bindaiya

ABSTRACT

Cassia tora, belonging to Fabaceae family, is a annual herb. It is a common plant found in all tropical parts of India. Height of Cassia tora is 30-90cm long, leaves is 3-4.5cm long, flowers are found in pair with five petals and pale yellow in colour, pods are 10-15cm long and sickle shaped and 30-50 seeds are present in a pod, stems have distinct smelling when its young. Leaves show the presence of polyphenols, emodin, amino acids, fatty acids, Flavonol glycoside. Seed contains anthraquinones, Brassinosteroids, Monoglycerides, phenolic glycoside. Stem bark contains anthraquinones, mannitol, β-sitosterol, glucose and choline. Flower, stem, leaves, seeds, root, stem bark are use therapeutically against in leprosy, ringworm, bronchitis, cardiac diseases, hepatic disorder, liver tonic, hemorrhoids, and ophthalmic, skin diseases. The ethanolic extract of stem bark of cassia tora was studied for wound healing activity in Wister albino rat by the method of wound model. Soframycin was used as a standard reference and ointment base are used as a control. Ethanolic extract of plant have been shown to possess good therapeutic potential and promoter of wound healing due to presence of active alkaloids and flavonoids. It was observed that the wound contraction ability of the extract was significantly greater than that of control, which was comparable to that of the reference standard Soframycin ointment.

Keywords: Cassia tora, Ethanolic extract of stem, Soframycin, wound healing activities, excision and Incision wound model.


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