Abstract

PHARMACODYNAMICS OF “BASTI- KARMA” – A REVIEW

Sapna Kumari Vishwas*, Manabjyoti Sarmah, K. K. Sharma, Parul Sharma

ABSTRACT

In the management of diseases the fundamental principles of the Ayurveda is Samshodhana (therapeutic purification), Samshamana (palliative treatment) and Nidana Parivarjana (avoid causative factors). Panchakarma presents a unique approach of Ayurveda with specially designed five procedures of internal purification of the body through the nearest possible route. Basti Chikitsa regarded as the prime treatment modality among the Panchakarma. Pharmacodynamics of Basti Karma includes biochemical and physiological effects of Basti Dravyas on body, which may be understood through absorption mechanism, neural stimulation mechanism, chemical stimulation mechanism and mechanical stimulation mechanism. The Basti Dravya may be absorbed directly or by diffusion, filtration and osmosis method. The Enteric Nervous System (ENS) works in synergism with the Central Nervous System (CNS), stimulation with Basti, either by chemo or mechano receptors may lead to activation of concerned part of CNS which precipitates result accordingly. Certain mechanical or chemical stimulation is responsible for nervous stimulation and thus produces the effect.

Keywords: Pharmacodynamics, Samshodhana, Samshamana, Nidana Parivarjana, synergism.