Abstract

OVERVIEW OF TRADITIONAL, PHYTOCHEMICAL, AND PHARMACOLOGICAL USES OF PULAI (ALSTONIA SCHOLARIS)

Richa Oktavia, Sestry Misfadhila and Harrizul Rivai*

ABSTRACT

Many herbal medicines have been used in various medical systems for the treatment and management of various diseases. Pulai plant (Alstonia scholaris) has been used in various traditional treatment systems to treat various diseases in humans. Phytochomically, this plant has been reported to contain various alkaloids, flavonoids, and phenolic acids. Pharmacologically this plant has been reported as an antimicrobial, antiamoebic, antidiarrheal, antiplasmodial, hepatoprotective, immunomodulatory, anticancer, antiasthmatic, free radical scavenging, antioxidant, analgesic, anti-inflammatory, anti-ulcer, anti-fertility, anti-fertility, and anti-wound healing activities. There are also reports available for this plant's traditional uses because of its cardiotonic, antidiabetic, and anti-rheumatic properties. Many isolated constituents of Alstonia scholaris have reports of pharmacological activity, which supports further pharmacological studies.

Keywords: Alstonia scholaris, Traditional Use, Phytochemistry, Pharmacology.