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Abstract

COMPARATIVE EFFICACY OF NEOMYCIN (NEOBIOTIC® AND ANTICIN®) AGAINST EXPERIMENTAL INFECTION WITH ESCHERICHIA COLI IN BROILER CHICKENS

Ashraf El-Komy* and Mohamed Aboubakr

ABSTRACT

This study was conducted to assess the efficacy of neomycin (Neobiotic® and Anticin)® in controlling the adverse effects of experimentally induced colibacillosis in broiler chickens. Two hundred, one-day old broiler chicks were used and randomly allocated into three experimental groups; group (1) uninfected-untreated, group (2) infected-untreated, group (3) infected-treated with neomycin (Neobiotic)® in the drinking water and group (4) infected-treated with neomycin (Anticin)® in the drinking water. The drug was given at dose level of 11 mg neomycin sulphate/kg b.wt/day for 5 consecutive days. Experimental colibacillosis was induced at 21-day of age by IM inoculation of Escherichia coli (E.coli) serotype O78. Clinical signs, mortalities, mean lesion scores, performance including body weight and feed conversion efficiency were recorded and evaluated. The Results showed that infected-neomycin treated chickens had less pronounced clinical signs, significant lower mortalities, higher body weight and better feed conversion than infected-untreated birds. In conclusion, neomycin administration (Neobiotic® and Anticin®) at 11 mg neomycin sulphate/kg b.wt /day for 5 consecutive days is efficacious for the treatment of colibacillosis in broiler chickens evident by improvement of all investigated parameters, and there was no significant changes between Neobiotic® and Anticin® and both products can be used as interchangeable drug in veterinary medicine practice especially in poultry.

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