Abstract

GASTROHEPATIC INVOLVEMENT IN COVID – 19: A COMPREHENSIVE REVIEW

Jeevan Chandra Pandey*, Dr. Pushpendra Kannojia, and Dr. Pankaj Mishra

ABSTRACT

The 2019 coronavirus disease outbreak (COVID-19), caused by the extreme acute respiratory coronavirus 2 syndrome (SARS-CoV-2), has drawn growing attention around the world. The aims of this paper are to investigate the pandemic's effect on patients with liver disease. Cases of liver dysfunction have been reported in patients with COVID-19 (mainly characterized by moderately elevated levels of serum aspartate aminotransferase. However, it is currently unclear whether the liver damage / dysfunction associated with COVID-19 is solely due to viral infection or other coexisting conditions, such as the use of potentially hepatotoxic drugs and the coexistence of systemic inflammatory response, hypoxia-induced respiratory distress syndrome, and multiple organ dysfunctions. In this study, we examine how COVID-19 affects the digestive system and liver using the various available statistical studies conducted in different parts of china. This review also discusses possible underlying mechanisms that relate COVID-19 to liver dysfunction, to promote potential COVID-19 drug growth, prevention, and control acts.

Keywords: Covid-19, Liver Dysfunction, SARS-CoV-2.