WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

ESTIMATION OF GUAIFENESIN BY UV VISIBLE SPECTROPHOTOMETER IN PHARMACEUTICAL SUBSTANCES AND PHARMACEUTICAL PRODUCT

Manasa Merugu*, B. Sai Teja, B. Kavya Sree, B. Pravallika and Ch. Navya Prashanthi

ABSTRACT

The present research work discuss the development of UV spectroscopic method for the estimation Guaifenesin. Simple, specific, accurate and cost effective spectroscopic method has been developed for the estimation of guaifenesin in bulk as well as formulation. The optimum condition for the analysis of the drug were established. The maximum wavelength (λmax) was found to be 209 nm. The validation was performed as per ICH guidelines for linearity accuracy, precision, LOD and LOQ. The method show high sensitivity with linearity in the range of 50-150 μg/ml and shows a linear relationship between the absorbance and concentration with coefficient of correlation 0.999. The regression of curve was y = 0.244x + 0.246. The precision of method was found to be good. The percentage recovery was found to be 99.57%. Good reproducibility was observed from precision with RDS <2%. The proposed method will be suitable for analysis of guaifenesin in bulk as well as pharmaceutical formulations in quality control purpose. Thus it was concluded that the proposed method is new, simple, cost, effective, safe, accurate, precise and environmental friendly.

Keywords: Guaifenesin UV spectroscopic, sensitive, validation, ICH guidelines.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More