Abstract

STUDY OF ANTHELMINTIC POTENTIAL OF ETHANOLIC EXTRACT OF ANNONA RETICULATA LINN LEAVES

Chavan Akshay B.* Chavan Rohankumar R., Mohite Swapnali A., Dhanavade Srushti S. and Pawar Subhash Y.

ABSTRACT

The aim of the present study was to evaluate the In-vitro Anthelmintic activity of ethanolic extract of leaves of Annona reticulata linn (Annonaceae) against worms Eisenia fetida. The various concentration range 10, 20, 30 mg/ml, of crude extracts and standards were studied for activity, by examination of paralysis and death time of the worms. Albendazole (20 mg/ml) is used as a standard drug and normal saline water as control. The leaves extract of Annona reticulata had shown a dose dependent inhibition of spontaneous motility (Paralysis) of earthworms. Thus, the present study indicates the leaves of the Annona reticulata linn possess dose dependent anthelmintic activity.

Keywords: Annona reticulata linn, Anthelmintic activity, Eisenia fetida, Albendazole.