A REVIEW STUDY ON- MEDICATED LOZENGES AS AN EFFECTIVE DOSAGE FORM
Abhijeet Sunil Kukde*, Varsha M. Barethiya and Dr. Gouri R. Dixit
ABSTRACT
In spite of several dosage forms available within the market place for effective action, the lozenges finds a special importance as they are the simplest dosage forms for formulating large dose of medicaments. The anatomy of mouth and cheek favours easy and effective systemic absorption of drug for better patient compliance and also especially for paediatrics and geriatrics patient because of their palatable taste imparted by the excipients. Lozenges are used for patients who cannot swallow solid oral dosage forms also as for medications designed to be released slowly to yield a continuing level of drug in the oral cavity. Lozenges are the flavoured medicated dosage forms intended to be administered and held in the mouth or pharynx containing one or more medicaments usually in the sweetened base. Lozenges are one of the very convenient and better innovative dosage form for oral confectionary products. Medicated lozenges enhances the retention time of the dosage form in mouth which increases bioavailability, reduces gastric irritation and bypasses first pass metabolism. Hence, Lozenges are an attractive, easily acceptable and most prominent dosage form for all the age group of population.
Keywords: Lozenges, sugar- bases, crystallization, medicaments, temperature.
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