Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS MAY ISSUE PUBLISHED
  • MAY 2020 Issue has been successfully launched on 1 May 2020.

Abstract

A REVIEW ON RNA INTERFERENCE [RNA I] TECHNOLOGY: A SIGNIFICANT GENE REGULATORY TOOL WITH ALARMING POTENTIAL IN SCIENTIFIC APPLICATIONS

Vyshnavi V. Rao* and Bhavana J.

ABSTRACT

RNA interference is a post-transcriptional gene silencing biotechnology tool. It is defined as endogenously induced gene silencing by miRNAs as well as gene silencing triggered by foreign dsRNA. It is also be defined as an RNA guided gene regulation pathway. RNAi has already been used as an effective gene knockdown tool. It is efficiently used to down regulate genes which are overexpressed in a disordered condition. Though it is widely accepted, RNAi possess certain limitations with respect to their non-specific effects and delivery into the mammalian cells. The use of high through put screening in RNAi genome scale research has been used to identify the genetic composition of certain phenotypes. This dsRNA mediated gene silencing system has facilitated the improvement of medical therapies and several biotechnological applications. Though RNAi as a technique is not yet full-fledged, it is a tool of volcanic potential in scientific community.

Keywords: RNA interference, post-transcriptional gene silencing, Si-RNA, mi-RNA.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More